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Dr. Axelrod was born and raised in Massachusetts, where her father was a general practice physician. Her interest in medicine grew from his influence, as she joined him in making house calls as a young girl, and enjoyed reading through his medical textbooks, finding her interest drawn to the chapters on microbiology, and bacteriology and immunology. She was pre-med at Wellesley College, where she was encouraged to pursue medical school by her Dean. She graduated from Cornell University Medical College, and spent a year of residency at Montefiore Hospital, transferring to Mount Sinai for the second year and Fellowship training (1969-1972). She was hired by Dr. Theodore VanItallie for the Infectious Disease Division of the St. Luke's Hospital Department of Medicine at the end of her fellowship, and was the head of the unit between 1976 and 1980.
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